Coverart for item
The Resource Prions and prion diseases : new developments, Jean-Michel Verdier, editor

Prions and prion diseases : new developments, Jean-Michel Verdier, editor

Label
Prions and prion diseases : new developments
Title
Prions and prion diseases
Title remainder
new developments
Statement of responsibility
Jean-Michel Verdier, editor
Contributor
Subject
Language
eng
Member of
Dewey number
579.2/9
Illustrations
illustrations
Index
index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
Verdier, Jean-Michel
Series statement
  • Protein biochemistry, synthesis, structure, and cellular functions
  • Protein science and engineering
http://library.link/vocab/subjectName
  • Prions
  • Prion diseases
Label
Prions and prion diseases : new developments, Jean-Michel Verdier, editor
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Contents
  • ""PRIONS AND PRION DISEASES""; ""PRIONS AND PRION DISEASES""; ""CONTENTS ""; ""PREFACE ""; ""NEUROPATHOLOGY OF HUMAN PRION DISEASES ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""THE ROLE OF NEUROPATHOLOGY ""; ""PERFORMING THE AUTOPSY ""; ""NEUROPATHOLOGICAL EXAMINATION""; ""A.) Macroscopy""; ""B.) Work-Up for Histological Evaluation ""; ""C.) Microscopic Assessment ""; ""I.) Spongiform Change of the Neuropil ""; ""a) In Sporadic Forms""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""II) Neuronal Death ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""
  • ""SYNAPTIC PATHOLOGY """"III.) Astroglial Proliferation ""; ""IV.) Microglial Activation ""; ""V.) PrP Amyloid Plaques ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VI.) Cerebellar Pathology ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms""; ""RELATIVE RESISTANCE OF HIPPOCAMPUS IN CJD ""; ""VII.) Detection of PrP ""; ""VIIa.) By Immunohistochemistry ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VIIb.) By histoblot and Paraffin-Embedded Tissue Blot ""
  • ""VIId.) By Western blot""""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VIII.) Co-deposition of other Abnormal Protein Aggregates in CJD ""; ""a) In Sporadic Forms ""; ""b) In Genetic Forms ""; ""c) In Acquired Forms ""; ""IX.) Differential Diagnoses from Autopsy Series ""; ""X.) Neuronal Systems and Their Clinico-Pathological Correlates ""; ""CONCLUSION ""; ""ACKNOWLEDGMENTS ""; ""REFERENCES ""; ""THE NATURE OF THE INFECTIOUS AGENTS: PRP MODELS OF RESISTANT SPECIES TO PRION DISEASES (DOG, RABBIT AND HORSES)""; ""Abstract""; ""1. Introduction""
  • ""2. MaterialsandMethods""""3. ResultsandDiscussion""; ""4. Conclusion""; ""Acknowledgments""; ""References""; ""INDUCING TRANSMISSIBLE PRION DISEASES WITH RECOMBINANT FIBRILS: A NEW CONCEPT ON GENESIS AND EVOLUTION OF INFECTIOUS PRIONS ""; ""ABSTRACT ""; ""GENERATING TRANSMISSIBLE PRION DISEASES DE NOVO ""; ""THE MECHANISM OF TRIGGERING PRION DISEASE BY RPRP AMYLOID FIBRILS ""; ""EXPERIMENTAL EVIDENCE SUPPORT THE SECOND MODEL ""; ""THE HYPOTHESIS OF DEFORMED TEMPLATING ""; ""CONFORMATIONAL SWITCHING WITHIN INDIVIDUAL AMYLOID FIBRILS AND STRAIN ADAPTATION PHENOMENON""
  • ""CROSS-TALK BETWEEN AMYLOIDOGENIC PROTEINS """"REFERENCES ""; ""SYNTHETIC PRIONS ""; ""ABSTRACT""; ""1. INTRODUCTION ""; ""2. STRATEGIES FOR DE NOVO MAMMALIAN PRIONS GENERATION ""; ""2.1. Cell-Free Assay Using Mammalian Prions ""; ""2.2. De Novo Generation of Prions by Mouse Transgenesis ""; ""2.3. In Vitro De Novo Prions by PMCA ""; ""2.4. De Novo Prions by Amyloid Seeding Assay ""; ""2.5. De Novo Prions by Annealing Technique ""; ""2.6. Concluding Remarks and New Emerging Techniques for Prion Detection and Generation ""; ""3. STRUCTURAL BIOLOGY OF NATURAL AND SYNTHETIC PRIONS""
Control code
ocn828140689
Dimensions
unknown
Extent
1 online resource (ix, 200 pages)
Form of item
online
Isbn
9781619427686
Other physical details
illustrations (some color)
Specific material designation
remote
System control number
(OCoLC)828140689
Label
Prions and prion diseases : new developments, Jean-Michel Verdier, editor
Publication
Bibliography note
Includes bibliographical references and index
Contents
  • ""PRIONS AND PRION DISEASES""; ""PRIONS AND PRION DISEASES""; ""CONTENTS ""; ""PREFACE ""; ""NEUROPATHOLOGY OF HUMAN PRION DISEASES ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""THE ROLE OF NEUROPATHOLOGY ""; ""PERFORMING THE AUTOPSY ""; ""NEUROPATHOLOGICAL EXAMINATION""; ""A.) Macroscopy""; ""B.) Work-Up for Histological Evaluation ""; ""C.) Microscopic Assessment ""; ""I.) Spongiform Change of the Neuropil ""; ""a) In Sporadic Forms""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""II) Neuronal Death ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""
  • ""SYNAPTIC PATHOLOGY """"III.) Astroglial Proliferation ""; ""IV.) Microglial Activation ""; ""V.) PrP Amyloid Plaques ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VI.) Cerebellar Pathology ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms""; ""RELATIVE RESISTANCE OF HIPPOCAMPUS IN CJD ""; ""VII.) Detection of PrP ""; ""VIIa.) By Immunohistochemistry ""; ""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VIIb.) By histoblot and Paraffin-Embedded Tissue Blot ""
  • ""VIId.) By Western blot""""a.) In Sporadic Forms ""; ""b.) In Genetic Forms ""; ""c.) In Acquired Forms ""; ""VIII.) Co-deposition of other Abnormal Protein Aggregates in CJD ""; ""a) In Sporadic Forms ""; ""b) In Genetic Forms ""; ""c) In Acquired Forms ""; ""IX.) Differential Diagnoses from Autopsy Series ""; ""X.) Neuronal Systems and Their Clinico-Pathological Correlates ""; ""CONCLUSION ""; ""ACKNOWLEDGMENTS ""; ""REFERENCES ""; ""THE NATURE OF THE INFECTIOUS AGENTS: PRP MODELS OF RESISTANT SPECIES TO PRION DISEASES (DOG, RABBIT AND HORSES)""; ""Abstract""; ""1. Introduction""
  • ""2. MaterialsandMethods""""3. ResultsandDiscussion""; ""4. Conclusion""; ""Acknowledgments""; ""References""; ""INDUCING TRANSMISSIBLE PRION DISEASES WITH RECOMBINANT FIBRILS: A NEW CONCEPT ON GENESIS AND EVOLUTION OF INFECTIOUS PRIONS ""; ""ABSTRACT ""; ""GENERATING TRANSMISSIBLE PRION DISEASES DE NOVO ""; ""THE MECHANISM OF TRIGGERING PRION DISEASE BY RPRP AMYLOID FIBRILS ""; ""EXPERIMENTAL EVIDENCE SUPPORT THE SECOND MODEL ""; ""THE HYPOTHESIS OF DEFORMED TEMPLATING ""; ""CONFORMATIONAL SWITCHING WITHIN INDIVIDUAL AMYLOID FIBRILS AND STRAIN ADAPTATION PHENOMENON""
  • ""CROSS-TALK BETWEEN AMYLOIDOGENIC PROTEINS """"REFERENCES ""; ""SYNTHETIC PRIONS ""; ""ABSTRACT""; ""1. INTRODUCTION ""; ""2. STRATEGIES FOR DE NOVO MAMMALIAN PRIONS GENERATION ""; ""2.1. Cell-Free Assay Using Mammalian Prions ""; ""2.2. De Novo Generation of Prions by Mouse Transgenesis ""; ""2.3. In Vitro De Novo Prions by PMCA ""; ""2.4. De Novo Prions by Amyloid Seeding Assay ""; ""2.5. De Novo Prions by Annealing Technique ""; ""2.6. Concluding Remarks and New Emerging Techniques for Prion Detection and Generation ""; ""3. STRUCTURAL BIOLOGY OF NATURAL AND SYNTHETIC PRIONS""
Control code
ocn828140689
Dimensions
unknown
Extent
1 online resource (ix, 200 pages)
Form of item
online
Isbn
9781619427686
Other physical details
illustrations (some color)
Specific material designation
remote
System control number
(OCoLC)828140689

Library Locations

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