Coverart for item
The Resource Fundamentals of early clinical drug development : from synthesis design to formulation, edited by Ahmed F. Abdel-Magid and Stéphane Caron, (electronic resource)

Fundamentals of early clinical drug development : from synthesis design to formulation, edited by Ahmed F. Abdel-Magid and Stéphane Caron, (electronic resource)

Label
Fundamentals of early clinical drug development : from synthesis design to formulation
Title
Fundamentals of early clinical drug development
Title remainder
from synthesis design to formulation
Statement of responsibility
edited by Ahmed F. Abdel-Magid and Stéphane Caron
Contributor
Subject
Language
eng
Summary
Using recent examples and important case studies, The Fundamentals of Early Clinical Drug Development: From Synthesis Design to Formulation demonstrates the central role℗¡that organic synthesis plays in the early clinical evaluation of potential drug candidates
Dewey number
615/.1
Illustrations
illustrations
Index
index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorDate
1947-
http://library.link/vocab/relatedWorkOrContributorName
  • Abdel-Magid, Ahmed F.
  • Caron, Stéphane
  • John Wiley & Sons
http://library.link/vocab/subjectName
  • Clinical pharmacology
  • Pharmaceutical technology
  • Drugs
Label
Fundamentals of early clinical drug development : from synthesis design to formulation, edited by Ahmed F. Abdel-Magid and Stéphane Caron, (electronic resource)
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Contents
Reflections on process research II / Edward J.J. Grabowski -- Development and scale-up of a heterocyclic cross-coupling for the synthesis of 5-(2-(3-methyl-3H-imidazol-4-yl)thieno(3,2-b)pyridin-7-yl)amino-2-methyl-1H-indol / John A. Ragan -- Large-scale enantioselective preparation of 2E,7E, 5S,6R, 5-hydroxy-6-methyl-8-phenyl-octa-2,7-dienoic acid, a key fragment for the formal total synthesis of the anti-tumor agent cryptophycin 52 / James Aikins ... [et al.] -- Efforts toward a commercially viable route and process to the synthesis of HIV PI GW640385X / John C. Roberts ... [et al.] -- Development of an asymmetric synthesis of ABT-100 / Albert W. Kruger ... [et al.] -- Asymmetric hydrogenation : a new route to pregabalin / Rex Jennings ... [et al.] -- Responsibilities of the process chemist : beyond synthetic organic chemistry / Stéphane Caron -- Outsourcing : the challenge of science, speed, and quality / Simone Andler-Burzlaff, Jason Bertola, and Roger E. Marti -- Automation and the changing face of process research in the pharmaceutical industry / Edward J. Delaney ... [et al.] -- Large scale synthesis : an engineering perspective / Joseph H. Childers, Jr. -- Synthesis and application of radioisotopes in pharmaceutical research and development / Larry E. Weaner and David C. Hoerr -- Selection of the drug form in exploratory development / George J. Quallich -- Strategies to control particle size of active pharmaceutical ingredients / David J. am Ende and Peter R. Rose -- Challenges in early formulation : turning drug substance into drug product / Mark H. Kleinman and Beeah Lee -- Intellectual property and early development / Maria I. Shchuka
Control code
ocm85821072
Dimensions
25 cm
Dimensions
unknown
Extent
xv, 323 p.
Form of item
online
Isbn
9780471692782
Isbn Type
(cloth)
Note
Wiley
Other control number
10.1002/0470043407
Other physical details
ill.
Reproduction note
Electronic reproduction.
Specific material designation
remote
System control number
(OCoLC)85821072
Label
Fundamentals of early clinical drug development : from synthesis design to formulation, edited by Ahmed F. Abdel-Magid and Stéphane Caron, (electronic resource)
Publication
Bibliography note
Includes bibliographical references and index
Contents
Reflections on process research II / Edward J.J. Grabowski -- Development and scale-up of a heterocyclic cross-coupling for the synthesis of 5-(2-(3-methyl-3H-imidazol-4-yl)thieno(3,2-b)pyridin-7-yl)amino-2-methyl-1H-indol / John A. Ragan -- Large-scale enantioselective preparation of 2E,7E, 5S,6R, 5-hydroxy-6-methyl-8-phenyl-octa-2,7-dienoic acid, a key fragment for the formal total synthesis of the anti-tumor agent cryptophycin 52 / James Aikins ... [et al.] -- Efforts toward a commercially viable route and process to the synthesis of HIV PI GW640385X / John C. Roberts ... [et al.] -- Development of an asymmetric synthesis of ABT-100 / Albert W. Kruger ... [et al.] -- Asymmetric hydrogenation : a new route to pregabalin / Rex Jennings ... [et al.] -- Responsibilities of the process chemist : beyond synthetic organic chemistry / Stéphane Caron -- Outsourcing : the challenge of science, speed, and quality / Simone Andler-Burzlaff, Jason Bertola, and Roger E. Marti -- Automation and the changing face of process research in the pharmaceutical industry / Edward J. Delaney ... [et al.] -- Large scale synthesis : an engineering perspective / Joseph H. Childers, Jr. -- Synthesis and application of radioisotopes in pharmaceutical research and development / Larry E. Weaner and David C. Hoerr -- Selection of the drug form in exploratory development / George J. Quallich -- Strategies to control particle size of active pharmaceutical ingredients / David J. am Ende and Peter R. Rose -- Challenges in early formulation : turning drug substance into drug product / Mark H. Kleinman and Beeah Lee -- Intellectual property and early development / Maria I. Shchuka
Control code
ocm85821072
Dimensions
25 cm
Dimensions
unknown
Extent
xv, 323 p.
Form of item
online
Isbn
9780471692782
Isbn Type
(cloth)
Note
Wiley
Other control number
10.1002/0470043407
Other physical details
ill.
Reproduction note
Electronic reproduction.
Specific material designation
remote
System control number
(OCoLC)85821072

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