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The Resource Computational methods for mass spectrometry proteomics, Ingvar Eidhammer ... [et al.], (electronic resource)

Computational methods for mass spectrometry proteomics, Ingvar Eidhammer ... [et al.], (electronic resource)

Label
Computational methods for mass spectrometry proteomics
Title
Computational methods for mass spectrometry proteomics
Statement of responsibility
Ingvar Eidhammer ... [et al.]
Contributor
Subject
Language
eng
Summary
Proteomics is the study of the subsets of proteins present in different parts of an organism and how they change with time and varying conditions. Mass spectrometry is the leading technology used in proteomics, and the field relies heavily on bioinformatics to process and analyze the acquired data. Since recent years have seen tremendous developments in instrumentation and proteomics-related bioinformatics, there is clearly a need for a solid introduction to the crossroads where proteomics and bioinformatics meet. "Computational Methods for Mass Spectrometry Proteomics" describes the different instruments and methodologies used in proteomics in a unified manner. The authors put an emphasis on the computational methods for the different phases of a proteomics analysis, but the underlying principles in protein chemistry and instrument technology are also described. This book is illustrated by a number of figures and examples, and contains exercises for the reader. Written in an accessible yet rigorous style, it is a valuable reference for both informaticians and biologists. "Computational Methods for Mass Spectrometry Proteomics" is suited for advanced undergraduate and graduate students of bioinformatics and molecular biology with an interest in proteomics. It also provides a good introduction and reference source for researchers new to proteomics, and for people who come into more peripheral contact with the field
Dewey number
572/.60285
Illustrations
illustrations
Index
index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
http://library.link/vocab/relatedWorkOrContributorName
Eidhammer, Ingvar
http://library.link/vocab/subjectName
  • Proteomics
  • Mass spectrometry
  • Bioinformatics
Label
Computational methods for mass spectrometry proteomics, Ingvar Eidhammer ... [et al.], (electronic resource)
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Color
multicolored
Contents
Protein, proteome, and proteomics -- Protein separation: 2D gel electrophoresis -- Protein digestion -- Peptide separation: HPLC -- Fundamentals of mass spectrometry -- Mass spectrometry: MALDI-TOF -- Protein identification and characterization by MS -- Tandem MS or MS/MS analysis -- Fragmentation models -- Identification and characterization by MS/MS -- Spectral comparisons -- Sequential comparison: de novo sequencing -- Database searching for de novo sequences -- Large-scale proteomics -- Quantitative MS-based proteomics -- Peptides to proteins -- Top-down proteomics -- Standards
Control code
ocn184983256
Dimensions
unknown
Extent
1 online resource (x, 284 p.)
Form of item
online
Isbn
9780470724293
Isbn Type
(electronic bk.)
Note
Wiley
Other control number
10.1002/9780470724309
Other physical details
ill
Specific material designation
remote
System control number
(OCoLC)184983256
Label
Computational methods for mass spectrometry proteomics, Ingvar Eidhammer ... [et al.], (electronic resource)
Publication
Bibliography note
Includes bibliographical references and index
Color
multicolored
Contents
Protein, proteome, and proteomics -- Protein separation: 2D gel electrophoresis -- Protein digestion -- Peptide separation: HPLC -- Fundamentals of mass spectrometry -- Mass spectrometry: MALDI-TOF -- Protein identification and characterization by MS -- Tandem MS or MS/MS analysis -- Fragmentation models -- Identification and characterization by MS/MS -- Spectral comparisons -- Sequential comparison: de novo sequencing -- Database searching for de novo sequences -- Large-scale proteomics -- Quantitative MS-based proteomics -- Peptides to proteins -- Top-down proteomics -- Standards
Control code
ocn184983256
Dimensions
unknown
Extent
1 online resource (x, 284 p.)
Form of item
online
Isbn
9780470724293
Isbn Type
(electronic bk.)
Note
Wiley
Other control number
10.1002/9780470724309
Other physical details
ill
Specific material designation
remote
System control number
(OCoLC)184983256

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